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Invitrogen™ PCDHGB5 Polyclonal Antibody
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Catalog No. PIPA568429
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100 μL
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PIPA568429 100 μL
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Catalog No. PIPA568429 Supplier Invitrogen™ Supplier No. PA568429
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Description

Rabbit Polyclonal Antibody

PCDHGB5 Polyclonal Antibody for IHC (P)

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHGB5
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene PCDHGB5
Gene Accession No. Q9Y5G0
Gene Alias PCDH-gamma-B5; PCDHGB5; protocadherin gamma subfamily B, 5; protocadherin gamma-B5
Gene Symbols PCDHGB5
Host Species Rabbit
Immunogen Synthesized peptide derived from human PCDHGB5.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56101
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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