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PCDHGC3/PCDH2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981130
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50-198-1130 100 μL
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Catalog No. 50-198-1130 Supplier Bioss Supplier No. BS11159R
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Description

Rabbit Polyclonal Antibody

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Specifications

Antigen PCDHGC3/PCDH2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PCDHGC3
Gene Accession No. Q9UN70
Gene Alias BOS_8246; Cadherin like 2; cadherin-like 2; PC 43; PC43; PC-43; PCDH 2; PCDH gamma C3; PCDH2; PCDH-gamma-C3; Pcdhgb6; PCDHGC 3; PCDHGC3; protocadherin 2; protocadherin 43; protocadherin gamma subfamily C, 3; Protocadherin gamma-C3; Protocadherin2; Protocadherin-2; Protocadherin43; Protocadherin-43
Gene Symbols PCDHGC3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PCDHGC3/PCDH2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5098
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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