Invitrogen™ PCDHGC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542717

Catalog No. PIPA542717

Description

Peptide sequence: ISEAVAPGTR FPLESAHDPD VGSNSLQTYE LSRNEYFALR VQTREDSTKY Sequence homology: Cow: 100%; Dog: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%.

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Specifications

• Antigen: PCDHGC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDHGC3
• Gene Alias: Cadherin like 2; cadherin-like 2; PC 43; PC43; PC-43; PCDH 2; PCDH gamma C3; PCDH2; PCDH-GAMMA-C3; Pcdhgb6; PCDHGC 3; PCDHGC3; protocadherin 2; protocadherin 43; protocadherin gamma subfamily C, 3; protocadherin gamma-C3; Protocadherin2; Protocadherin-2; Protocadherin43; protocadherin-43
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5098
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9UN70
• Gene Symbols: PCDHGC3
• Immunogen: Synthetic peptide directed towards the N-terminal of human PCDHGC3 (aa 144-193).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov