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Invitrogen™ PCDHGC3 Polyclonal Antibody
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Catalog No. PIPA542717
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100 μL
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PIPA542717 100 μL
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Catalog No. PIPA542717 Supplier Invitrogen™ Supplier No. PA542717
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Description

Rabbit Polyclonal Antibody

Peptide sequence: ISEAVAPGTR FPLESAHDPD VGSNSLQTYE LSRNEYFALR VQTREDSTKY Sequence homology: Cow: 100%; Dog: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%.

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHGC3
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PCDHGC3
Gene Accession No. Q9UN70
Gene Alias Cadherin like 2; cadherin-like 2; PC 43; PC43; PC-43; PCDH 2; PCDH gamma C3; PCDH2; PCDH-GAMMA-C3; Pcdhgb6; PCDHGC 3; PCDHGC3; protocadherin 2; protocadherin 43; protocadherin gamma subfamily C, 3; protocadherin gamma-C3; Protocadherin2; Protocadherin-2; Protocadherin43; protocadherin-43
Gene Symbols PCDHGC3
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human PCDHGC3 (aa 144-193).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5098
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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