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PCDHGC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501726661 Shop All Proteintech Group Inc Products
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50-172-6661 150 μL
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Catalog No. 50-172-6661 Supplier Proteintech Group Inc Supplier No. 108571AP150UL
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Description

Rabbit Polyclonal Antibody

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Specifications

Antigen PCDHGC3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene PCDHGC3
Gene Accession No. Q9UN70
Gene Alias PC 43, PC43, PCDH GAMMA C3, PCDH2, PCDHGC3, Protocadherin 2, Protocadherin 43, Protocadherin gamma C3
Gene Symbols PCDHGC3
Host Species Rabbit
Immunogen PCDHGC3 Fusion Protein Ag1243
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116782, 5098, 93706
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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