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PCDHGC5 Mouse anti-Human, Clone: OTI1D7, lyophilized, TrueMAB™
SDP

Catalog No. 501668499
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100 μg
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50-166-8499 100 μg
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Catalog No. 50-166-8499 Supplier OriGene Supplier No. CF807814
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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Specifications

Antigen PCDHGC5
Applications Western Blot
Classification Monoclonal
Clone OTI1D7
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene PCDHGC5
Gene Accession No. Q9Y5F6
Gene Alias PCDH-GAMMA-C5
Gene Symbols PCDHGC5
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 35-258 of human PCDHGC5 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56097
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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