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Invitrogen™ PCGF6 Polyclonal Antibody
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Catalog No. PIPA5113770
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100 μL
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PIPA5113770 100 μL
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Catalog No. PIPA5113770 Supplier Invitrogen™ Supplier No. PA5113770
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TQPLYNISAN EGTGHFKPLE KKFVRVSGEA TIGHVEKFLR RKMGLDPACQ For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Human: 100%.

Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF6 (polycomb group ring finger 6), also known as MBLR or RNF134, is a 350 amino acid nuclear protein that is ubiquitously expressed and contains one RING-type zinc finger. PCGF6 acts as a transcriptional repressor and regulates the level of histone H3K4Me3 by activating SmcY histone demethylase. PCGF6 exists as two alternatively spliced isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCGF6
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PCGF6
Gene Accession No. Q9BYE7
Gene Alias 4933407A11Rik; AI604840; Mblr; Mel18 and Bmi1-like RING finger; Mel18- and Bmi1-like RING finger protein; Mel18 and Bmi1-like RING finger protein; Pcgf6; polycomb group ring finger 6; polycomb group RING finger protein 6; RING finger protein 134; RNF134
Gene Symbols PCGF6
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human PCGF6.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84108
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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