Invitrogen™ PCLO Monoclonal Antibody (6H9-B6), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545257

Catalog No. PIMA545257

Description

1 μg/mL of MA5-45257 was sufficient for detection of Piccolo in 20 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat IgG:HRP as the secondary antibody. Detects approximately 550kDa. No cross-reactivity to Bassoon.

The protein encoded by the PCLO gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PCLO
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: Q9JKS6, Q9QYX7, Q9Y6V0
• Gene Symbols: PCLO
• Immunogen: Full length recombinant protein (GenBank ID: BC001304.1).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 6H9-B6
• Conjugate: APC
• Gene: PCLO
• Gene Alias: Acz; Aczonin; brain-derived HLMN protein; KIAA0559; LOW QUALITY PROTEIN: protein piccolo; multidomain presynaptic cytomatrix protein; multidomain presynaptic cytomatrix protein Piccolo; PCH3; PCLO; piccolo (presynaptic cytomatrix protein); piccolo presynaptic cytomatrix protein; Pico; presynaptic cytomatrix protein; protein piccolo
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 26875, 27445, 56768
• Content And Storage: 4°C
• Form: Liquid