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Invitrogen™ PCMT1 Monoclonal Antibody (OTI2A9)
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Catalog No. PIMA527236
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100 μL
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PIMA527236 100 μL
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Catalog No. PIMA527236 Supplier Invitrogen™ Supplier No. MA527236
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Description

Mouse Monoclonal Antibody

PCMT1 Monoclonal Antibody for Western Blot, IHC (P)

Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCMT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2A9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PCMT1
Gene Accession No. P22061
Gene Alias C79501; L-isoaspartyl protein carboxyl methyltransferase; PCM; PCMT1; PIMT; protein carboxyl methyltransferase; protein L-isoaspartyl/D-aspartyl methyltransferase; Protein-beta-aspartate methyltransferase; protein-L-isoaspartate (D-aspartate) O-methyltransferase; protein-L-isoaspartate (D-aspartate) O-methyltransferase 1; protein-L-isoaspartate(D-aspartate) O-methyltransferase
Gene Symbols PCMT1
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 60-285 of PCMT1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5110
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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