PCNA Mouse anti-Human, Mouse, Rat, Clone: 1157CT1.1.3, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of human PCNA.

Supplier:  Abnova Corporation MAB12342

Catalog No. 89-934-739

Description

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq]

Specifications

• Antigen: PCNA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:25) Western Blot (1:2000) The optimal working dilution should be determined by the end user.
• Gene Alias: MGC8367
• Host Species: Mouse
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5111
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Clone: 1157CT1.1.3
• Description: Mouse monoclonal antibody raised against synthetic peptide of human PCNA.
• Formulation: In PBS (0.09% sodium azide)
• Gene Symbols: PCNA
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 236-261 at C-terminus region of human PCNA.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid