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PCP4/PEP-19 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981270
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50-198-1270 100 μL
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Catalog No. 50-198-1270 Supplier Bioss Supplier No. BS11326R
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Rabbit Polyclonal Antibody

PCP-4 (Purkinje cell protein 4), also known as PCP4, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer′s disease and Huntington′s disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.

Specifications

Antigen PCP4/PEP-19
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PCP4
Gene Accession No. P48539
Gene Alias brain specific polypeptide PEP19; Brain-specific antigen PCP-4; Brain-specific polypeptide PEP-19; Calmodulin regulator protein PCP4; P16Rimb19; PCP4; Pcp-4; Pep19; pep-19; PEPZ19; Purkinje cell protein 4
Gene Symbols PCP4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PCP4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5121
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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