Invitrogen™ PCSK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA120317

Catalog No. PIPA120317

Description

PA1-20317 detects PC1 in human, rat and non-human primate samples.

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.

Specifications

• Antigen: PCSK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCSK1
• Gene Alias: Att-1; Bdp; BMIQ12; EC 3.4.21.93; Furin homolog; LOW QUALITY PROTEIN: neuroendocrine convertase 1; NEC 1; NEC1; Nec-1; Neuroendocrine convertase 1; PC1; PC3; PCSK1; Phpp-1; Prohormone convertase 1; prohormone convertase 1/3; prohormone convertase 3; propeptide-processing protease; Proprotein convertase 1; proprotein convertase subtilisin/kexin type 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I; SPC3
• Host Species: Rabbit
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Rabbit, Monkey
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: Conc. Not Determined
• Formulation: Whole serum with 0.09% sodium azide
• Gene Accession No.: P28840, P29120
• Gene Symbols: PCSK1
• Immunogen: Recombinant, full length, rabbit PC1.
• Regulatory Status: RUO
• Gene ID (Entrez): 100345424, 25204, 5122
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov