PCSK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6400	Proteintech Group Inc 105531AP150UL	150 μL

Description

The subtilisin-like prohormone convertase (PC) family is a group of cellular enzymes that cleave most prohormones and neuropeptide precursors. Numerous other cellular proteins, some viral proteins, and bacterial toxins that are transported by the constitutive secretory pathway are also targeted for maturation by PCs. PC family members share structural similarities, which include a heterogeneous approximately10 kDa amino-terminal proregion, a highly conserved approximately55 kDa subtilisin-like catalytic domain, and carboxyl-terminal domain that is heterogeneous in length and sequence. These enzymes become catalytically active following proregion cleavage within the appropriate cellular compartment. The subcellular localization of PC family members varies. Immunolocalization studies show that PC1 is found in the perinuclear region as well as the trans-Golgi network, whereas PC2 can be found in the trans-Golgi network as well as diffusely distributed in the peripheral cytoplasm.

Specifications

• Antigen: PCSK2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P16519, P21661, P28841
• Gene ID (Entrez): 18549, 25121, 5126
• Immunogen: PCSK2 Fusion Protein Ag0852
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PCSK2

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: KEX2 like endoprotease 2, NEC 2, NEC2, Neuroendocrine convertase 2, PC2, PCSK2, Prohormone convertase 2, Proprotein convertase 2, SPC2
• Gene Symbols: PCSK2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody