Invitrogen™ PCSK6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532966

Catalog No. PIPA532966

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Rat, Bovine, Elephant, Horse, Rabbit (100%); Gibbon, Mouse, Dog, Panda, Pig (93%); Turkey, Chicken (86%). Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: PCSK6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCSK6
• Gene Alias: C86343; im:7140527; kexin-like protease PC7A; PACE4; Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; Pcsk6; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin - like endoprotease; Subtilisin/kexin-like protease PACE4; subtilisin-like proprotein convertase 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100057677, 100347173, 25507, 5046, 524684
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P29122, Q63415
• Gene Symbols: PCSK6
• Immunogen: Synthetic 14 amino acid peptide from Cys-rich motif (CRM) region of human PACE4.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat, Rabbit, Monkey, Bovine, Horse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov