Invitrogen™ PCSK6 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142420

Catalog No. PIPA5142420

Description

Additional Information: This antibody is expected to recognize reported isoforms a, b, g, h (NP_002561.1; NP_612192.1; NP_612193.1; NP_612194.1 resp.). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: PCSK6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCSK6
• Gene Alias: C86343; im:7140527; kexin-like protease PC7A; PACE4; Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; Pcsk6; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin - like endoprotease; Subtilisin/kexin-like protease PACE4; subtilisin-like proprotein convertase 4
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 5046
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P29122
• Gene Symbols: PCSK6
• Immunogen: Peptide with sequence PDCEPGTYFDSE.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG