Invitrogen™ PCSK9 Monoclonal Antibody (410420)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524149

Catalog No. PIMA524149

Description

This antibody detects the mature form of human Proprotein Convertase 9/PCSK9 in direct ELISAs and Western blots. This antibody does not cross-react with recombinant human (rh) PCSK1, rhPCSK7, or recombinant mouse PCSK9. Reconstitute at 0.5 mg/mL in sterile PBS.

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Specifications

• Antigen: PCSK9
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8NBP7
• Gene Symbols: PCSK9
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Proprotein Convertase 9/PCSK9 isoform 1 Arg29-Gln692.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot
• Clone: 410420
• Conjugate: Unconjugated
• Gene: PCSK9
• Gene Alias: AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 255738
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized