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Invitrogen™ PCSK9 Monoclonal Antibody (499911)
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Catalog No. PIMA524211
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100 μg
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Catalog No. Quantity
PIMA524211 100 μg
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Catalog No. PIMA524211 Supplier Invitrogen™ Supplier No. MA524211
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Description

Rat Monoclonal Antibody

In Western blots, 10% cross-reactivity with recombinant mouse PCSK9 is observed and no cross-reactivity with recombinant human (rh) PCSK1 or rhPCSK7 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCSK9
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 499911
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene PCSK9
Gene Accession No. Q8NBP7
Gene Alias AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9
Gene Symbols PCSK9
Host Species Rat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Proprotein Convertase 9/PCSK9 Arg29-Gln692.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 255738
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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