PD-1 Antibody (PDCD1/922), PE/Atto594, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP247805PEATT594

Catalog No. N247805P594

Description

PD-1 Monoclonal specifically detects PD-1 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: PD-1
• Classification: Monoclonal
• Conjugate: PE/ATTO 594
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: PDCD1
• Immunogen: Recombinant full-length human PD-1 protein (Uniprot: Q15116)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: PDCD1/922
• Dilution: Flow Cytometry
• Gene Alias: CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Apoptosis, Phospho Specific, Protein Phosphatase, Stem Cell Markers
• Gene ID (Entrez): 5133.0
• Target Species: Human
• Isotype: IgG1 κ