PD-1/CD279 Mouse anti-Human, Mouse, Rat, Clone: 4H4D1, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 662201IG150UL

Catalog No. 50-100-3189

Description

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Specifications

• Antigen: PD-1/CD279
• Classification: Monoclonal
• Concentration: 1.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q02242, Q15116
• Gene Symbols: PDCD1
• Immunogen: PD-1/CD279 Fusion Protein Ag12470
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4H4D1
• Conjugate: Unconjugated
• Gene: PDCD1
• Gene Alias: CD279, hPD 1, hPD l, PD1, PD-1, PD-1/CD279, PDCD1, programmed cell death 1, Protein PD 1, SLEB2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 18566, 301626, 5133
• Content And Storage: -20°C
• Form: Liquid