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Tocris Bioscience™ PD 158780

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Quantity:
10 mg
50 mg
Description
Potent inhibitor of ErbB receptor family tyrosine kinases (IC50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively) that does not inhibit FGF or PDGF-mediated tyrosine phosphorylation. Induces G1 cell cycle arrest in MCF10A cells and is antiproliferative in A431 human epidermal carcinoma cells.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 330.18 |
Purity | >99% |
Molecular Weight (g/mol) | 330.19 |
Chemical Name or Material | PD 158780 |
Safety and Handling
Recommended Storage | Store at -20°C |
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