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  7. PD 158780, Tocris Bioscience™

PD 158780, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
171179-06-9
C14H12BrN5
330.19
MFCD00942160
KFHMLBXBRCITHF-UHFFFAOYSA-N
n4-3-bromophenyl-n6-methylpyrido 3,4-d pyrimidine-4,6-diamine, chembl53753, insolution pd 158780, 4-n-3-bromophenyl-6-n-methylpyrido 3,4-d pyrimidine-4,6-diamine, 4-3-bromoanilino-6-methylaminopyrido 3,4-d pyrimidine, 4-3-bromophenyl amino-6-methylamino pyrido 3,4-d pyrimidine, 4-3-bromophenyl amino-6-methylamino-pyrido 3,4-d pyridimine, n4-3-bromophenyl-n6-methyl-pyrido 3,4-d pyrimidine-4,6-diamine, pyrido 3,4-d pyrimidine-4,6-diamine, n4-3-bromophenyl-n6-methyl
4707
N4-(3-bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
CNC1=NC=C2N=CN=C(NC3=CC(Br)=CC=C3)C2=C1
This item is not returnable. View return policy
171179-06-9
C14H12BrN5
330.19
MFCD00942160
KFHMLBXBRCITHF-UHFFFAOYSA-N
n4-3-bromophenyl-n6-methylpyrido 3,4-d pyrimidine-4,6-diamine, chembl53753, insolution pd 158780, 4-n-3-bromophenyl-6-n-methylpyrido 3,4-d pyrimidine-4,6-diamine, 4-3-bromoanilino-6-methylaminopyrido 3,4-d pyrimidine, 4-3-bromophenyl amino-6-methylamino pyrido 3,4-d pyrimidine, 4-3-bromophenyl amino-6-methylamino-pyrido 3,4-d pyridimine, n4-3-bromophenyl-n6-methyl-pyrido 3,4-d pyrimidine-4,6-diamine, pyrido 3,4-d pyrimidine-4,6-diamine, n4-3-bromophenyl-n6-methyl
4707
N4-(3-bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
CNC1=NC=C2N=CN=C(NC3=CC(Br)=CC=C3)C2=C1

Description

Potent ErbB receptor family inhibitor

Potent inhibitor of ErbB receptor family tyrosine kinases (IC50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively) that does not inhibit FGF or PDGF-mediated tyrosine phosphorylation. Induces G1 cell cycle arrest in MCF10A cells and is antiproliferative in A431 human epidermal carcinoma cells.
Quantity 50 mg
Formula Weight 330.18
Percent Purity >99%
Chemical Name or Material PD 158780

Safety and Handling

Recommended Storage : Store at -20°C