Invitrogen™ PDC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578415

Catalog No. PIPA578415

Description

Positive Control: mouse eye Predicted Reactivity: Human (100%), Rat (87%), Dog (93%), Cat (94%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PDC encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. PDC is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: PDC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDC
• Gene Alias: 33 kDa phototransducing protein; 33DPTP; G beta gamma binding protein; MEKA; MEKA protein; Pdc; PHD; PhLOP; PhLP; Phosducin; phosducin-like orphan protein; Phototransducing protein, 33 kDa (phosducin); Protein MEKA; Rod photoreceptor 1; Rpr1; RPR-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20028, 5132
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.06 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P20941, Q9QW08
• Gene Symbols: PDC
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Phosducin/PDC. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG