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Invitrogen™ PDC Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5116596
Description
Positive Samples: Mouse eye, Rat eye Immunogen sequence: MEEAKSQSLE EDFEGQATHT GPKGVINDWR KFKLESQDSD SIPPSKKEIL RQMSSPQSRN GKDSKERVSR KMSIQEYELI HKEKEDENCL RKYRRQCMQD MHQKLSFGPR YGFVYELETG KQFLETIEKE LKITTIVVHI YEDGIKGCDA LNSSLTCLAA EYPIVKFCKI KASNTGAGDR FSLDVLPTLL IYKGGELISN FISVAEQFAE EFFAGDVESF LNEYGLLPER EVHVLEHTKI EEEDVE.
PDC encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. PDC is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications
PDC | |
Polyclonal | |
Unconjugated | |
PDC | |
33 kDa phototransducing protein; 33DPTP; G beta gamma binding protein; MEKA; MEKA protein; Pdc; PHD; PhLOP; PhLP; Phosducin; phosducin-like orphan protein; Phototransducing protein, 33 kDa (phosducin); Protein MEKA; Rod photoreceptor 1; Rpr1; RPR-1 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
20028, 25343 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot | |
1.33 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P20942, Q9QW08 | |
PDC | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PDC (NP_0025883). | |
100 μL | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
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