PDCD1 Mouse anti-Human, Clone: SPM597, Abnova™

Mouse monoclonal antibody raised against full length recombinant human PDCD1.

Supplier:  Abnova Corporation MAB13137

Catalog No. 89-934-746

Description

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq]

Specifications

• Antigen: PDCD1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (0.5-1 ug/10⁶ cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Alias: CD279/PD1/SLEB2/hPD-1/hPD-l
• Host Species: Mouse
• Purification Method: Protein A/G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5133
• Content And Storage: Store at 4°C.
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Clone: SPM597
• Description: Mouse monoclonal antibody raised against full length recombinant human PDCD1.
• Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
• Gene Symbols: PDCD1
• Immunogen: Recombinant protein corresponding to full length human PDCD1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid