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PDCD10/CCM3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501568706
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50-156-8706 10 μL
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Catalog No. 50-156-8706 Supplier Bethyl Laboratories, Inc Supplier No. A304798AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Chicken

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

Antigen PDCD10/CCM3
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene PDCD10
Gene Accession No. Q9BUL8
Gene Alias CCM3, TFAR15
Gene Symbols PDCD10
Host Species Rabbit
Immunogen Between 75 and 125
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11235
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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