Invitrogen™ PDCD10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555503

Catalog No. PIPA555503

Description

Immunogen sequence: MRMTMEEMKN EAETTSMVSM PLYAVMYPVF NELERVNLSA AQTLRAAFIK AEKENPGLTQ DIIMK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 92%.

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: PDCD10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pdcd10
• Gene Alias: 2410003B13Rik; apoptosis-related protein 15; CCM3; Cerebral cavernous malformations 3 protein; MGC1212; MGC24477; PDCD 10; PDCD10; programmed cell death 10; programmed cell death protein 10; TF-1 cell apoptosis-related protein 15; Tfa15; TFAR15
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11235
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BUL8
• Gene Symbols: Pdcd10
• Immunogen: Recombinant protein corresponding to Human PDCD10. Recombinant protein control fragment (Product #RP-92030).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG