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Invitrogen™ PDCD2 Monoclonal Antibody (DHIC2-5H10)
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Catalog No. PIMA516135
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100 μL
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PIMA516135 100 μL
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Catalog No. PIMA516135 Supplier Invitrogen™ Supplier No. MA516135
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Description

Mouse Monoclonal Antibody

PDCD2 Monoclonal Antibody for IHC (F), ICC/IF, Flow

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDCD2
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunocytochemistry
Classification Monoclonal
Clone DHIC2-5H10
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.05% sodium azide
Gene Pdcd2
Gene Accession No. Q16342
Gene Alias AI528543; hypothetical protein MGC63685; Pcd2; PDCD2; programmed cell death 2; programmed cell death protein 2; RP8; RP-8; zgc:63685; zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8; ZMYND7
Gene Symbols Pdcd2
Host Species Mouse
Immunogen Human pancreatic enriched duct cells.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5134
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM
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