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Invitrogen™ PDCD2 Polyclonal Antibody
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Catalog No. PIPA530256
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100 μL
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PIPA530256 100 μL
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Catalog No. PIPA530256 Supplier Invitrogen™ Supplier No. PA530256
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HCT116. Predicted reactivity: Mouse (86%), Rat (86%), Pig (89%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDCD2
Applications Western Blot
Classification Polyclonal
Concentration 0.82 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Pdcd2
Gene Accession No. Q16342
Gene Alias AI528543; hypothetical protein MGC63685; Pcd2; PDCD2; programmed cell death 2; programmed cell death protein 2; RP8; RP-8; zgc:63685; zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8; ZMYND7
Gene Symbols Pdcd2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PDCD2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5134
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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