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PDCD6 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA527639
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100 μL
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PIPA527639 100 μL
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Catalog No. PIPA527639 Supplier Thermo Scientific Supplier No. PA527639

Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, HeLa nucleus. Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (88%), Xenopus laevis (86%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

An increased intracellular Ca2+ concentration induces apoptotic cell death. Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge. ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDCD6
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.62 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Pdcd6
Gene Accession No. O75340
Gene Alias Alg2; alg-2; ALG-257; Apoptosis-linked gene 2 protein; Apoptosis-linked gene 2 protein homolog; AV299538; MA-3; PDCD6; PEF1B; PMP41; probable calcium-binding protein ALG-2; programmed cell death 6; programmed cell death protein 6; PS2
Gene Symbols Pdcd6
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 191 of Human PDCD6
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10016
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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