PDE10A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA131145

Catalog No. PA131145

Description

Recommended positive controls: For western blot - Rat brain and pancreas.

Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.

Specifications

• Antigen: PDE10A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE10A
• Gene Alias: ADSD2; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; FLJ11894; FLJ25677; HSPDE10A; IOLOD; LINC00473; PDE10A; PDE10A19; PDE10A2 brain-specific isoform; Pde10a3; phosphodiesterase 10A; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7); testis-specific phosphodiesterase PDE10A2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10846, 23984, 63885
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.70 mg/mL
• Formulation: tris glycine with 0.5% BSA, 30% glycerol and 0.02% Sodium azide, 0.02% thimerosal; pH 7.4-7.9
• Gene Accession No.: Q8CA95, Q9QYJ6, Q9Y233
• Gene Symbols: PDE10A
• Immunogen: Synthetic peptide (Human) against a common sequence near the 250-325 amino acids downstream from the N terminal region of PDE10A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG