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Invitrogen™ PDE11A Polyclonal Antibody
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Catalog No. PIPA532968
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50 μg
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PIPA532968 50 μg
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Catalog No. PIPA532968 Supplier Invitrogen™ Supplier No. PA532968
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Hamster, Elephant, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Pufferfish, Zebrafish (100%); Platypus, Xenopus, Stickleback (94%); Dog (88%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE11A
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene PDE11A
Gene Accession No. P0C1Q2, Q8VID6, Q9HCR9
Gene Alias 6330414F14Rik; A630086N24Rik; cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; cAMP and cGMP phosphodiesterase 11A; Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; FLJ23693; Gm350; MGC133355; MGC133356; Pde11a; PDE11A1; phosphodiesterase 11A; PPNAD2
Gene Symbols PDE11A
Host Species Rabbit
Immunogen Synthetic 17 amino acid peptide from internal region of human PDE11A.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100053692, 100341520, 100738835, 100756511, 140928, 241489, 424133, 50940, 524446, 561338
Target Species Human, Mouse, Rat, Rabbit, Monkey, Bovine, Hamster, Pig, Horse, Chicken, Zebrafish, Bat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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