Invitrogen™ PDE1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587915

Catalog No. PIPA587915

Description

Immunogen sequence: EASKAETSSY VASSSTTIVG LHIADALRRS NTKGSMSDGS YSPDYSLAAV DLKSFKNNLV DIIQQNKERW KELAAQGESD LHKNSEDLVN AEEKHDETHS; Positive Samples: Mouse heart, Mouse brain, Mouse kidney, Rat heart, Rat brain.

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1)that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001).

Specifications

• Antigen: PDE1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE1A
• Gene Alias: 3'-RACE clone 8 phosphodiesterase 1A; 3-RACE clone 8 phosphodiesterase 1A; 3'-RACEclone8phosphodiesterase1A; 3-RACEclone8phosphodiesterase1A; 61 kDa Cam-PDE; AI987702; AW125737; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; cam-PDE 1A; CAM-PDE-1A; HCAM1; hCam-1; HS MGC26303; HSPDE1A; MGC26303; Pde1a; phosphodiesterase 1A; phosphodiesterase 1A, calmodulin-dependent; phosphodiesterase-1A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18573, 5136, 81529
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P54750, Q61481
• Gene Symbols: PDE1A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 446-545 of human PDE1A (NP_0050102).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG