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Invitrogen™ PDE1B Monoclonal Antibody (5C4A3)
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Catalog No. PIMA517147
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100 μg
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PIMA517147 100 μg
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Catalog No. PIMA517147 Supplier Invitrogen™ Supplier No. MA517147
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Mouse Monoclonal Antibody

MA5-17147 targets PDE1B in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Rat samples. The MA5-17147 immunogen is purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli. MA5-17147 detects PDE1B which has a predicted molecular weight of approximately 61.4kDa.

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE1B
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 5C4A3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Pde1b
Gene Accession No. Q01064, Q01066
Gene Alias 63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); EGK_03739; epididymis secretory sperm binding protein Li 79p; HEL-S-79p; PDE 1B; Pde1b; Pde1b1; PDES 1B; PDES1B; Phosphodiesterase; phosphodiesterase 1B; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
Gene Symbols Pde1b
Host Species Mouse
Immunogen Purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29691, 5153
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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