Invitrogen™ PDE1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553817

Catalog No. PIPA553817

Description

Immunogen sequence: TFSVLTDVAE KSVQPLADED SKSKNQPSFQ WRQPSLDVEV GDPNPDVVSF RSTWVKRIQE NKQKWKERAA SGITNQMSID ELSPCEEEAP PSPAEDEHNQ NGN Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: PDE1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pde1b
• Gene Alias: 63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); EGK_03739; epididymis secretory sperm binding protein Li 79p; HEL-S-79p; PDE 1B; Pde1b; Pde1b1; PDES 1B; PDES1B; Phosphodiesterase; phosphodiesterase 1B; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5153
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q01064
• Gene Symbols: Pde1b
• Immunogen: Recombinant protein corresponding to Human PDE1B. Recombinant protein control fragment (Product #RP-92038).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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