PDE2A Monoclonal Antibody (OTI5D9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA502318

Catalog No. 50-167-3381

Description

PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) and three isoforms of PDE2A have been reported (PDE2A1, PDE2A2 and PDE2A3) which arise from a single gene by alternative splicing events. PDE2A can degrade both cAMP and cGMP, but degrades cGMP with greater efficacy. PDE2A is expressed in a variety of tissue types, with greatest expression in the brain, where it is localized in the cerebellum and neocortex. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transport across the endothelial cell barrier.

Specifications

• Antigen: PDE2A
• Classification: Monoclonal
• Concentration: 0.52 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O00408
• Gene Symbols: PDE2A
• Immunogen: Full length human recombit protein of human PDE2A produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: OTI5D9
• Conjugate: Unconjugated
• Gene: PDE2A
• Gene Alias: CGS-PDE, PDE2A1, PED2A4, cGSPDE
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5138
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid