PDE2A Mouse anti-Human, Clone: OTI2F1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF502354

Catalog No. 50-166-1265

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) and three isoforms of PDE2A have been reported (PDE2A1, PDE2A2 and PDE2A3) which arise from a single gene by alternative splicing events. PDE2A can degrade both cAMP and cGMP, but degrades cGMP with greater efficacy. PDE2A is expressed in a variety of tissue types, with greatest expression in the brain, where it is localized in the cerebellum and neocortex. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transport across the endothelial cell barrier.

Specifications

• Antigen: PDE2A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PDE2A
• Gene Alias: CGS-PDE, PDE2A1, PED2A4, cGSPDE
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5138
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Clone: OTI2F1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O00408
• Gene Symbols: PDE2A
• Immunogen: Full length human recombit protein of human PDE2A produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1