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Invitrogen™ PDE2A Polyclonal Antibody
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Catalog No. PIPA5118908
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100 μL
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Catalog No. Quantity
PIPA5118908 100 μL
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Catalog No. PIPA5118908 Supplier Invitrogen™ Supplier No. PA5118908
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PDE2A.

PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) and three isoforms of PDE2A have been reported (PDE2A1, PDE2A2 and PDE2A3) which arise from a single gene by alternative splicing events. PDE2A can degrade both cAMP and cGMP, but degrades cGMP with greater efficacy. PDE2A is expressed in a variety of tissue types, with greatest expression in the brain, where it is localized in the cerebellum and neocortex. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transport across the endothelial cell barrier.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE2A
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PDE2A
Gene Accession No. O00408, Q01062, Q922S4
Gene Alias c-GMP stimulated phosphodiesterase; cGMP-dependent 3',5'-cyclic phosphodiesterase; cGMP-stimulated cyclic nucleotide phosphodiesterase; cGMP-stimulated phosphodiesterase 1; cGMP-stimulated phosphodiesterase 2; cGMP-stimulated phosphodiesterase 4; cGSPDE; CGS-PDE; cyclic GMP stimulated phosphodiesterase; cyclic GMP-stimulated phosphodiesterase; cyclic nucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase 2a; Pde2; Pde2a; PDE2A1; Pde2a2; PED2A4; phosphodiesterase 2A; phosphodiesterase 2A, cGMP-stimulated
Gene Symbols PDE2A
Host Species Rabbit
Immunogen A synthesized peptide derived from human PDE2A(Accession O00408), corresponding to amino acid residues L825-Q875.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 207728, 5138, 81743
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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