Invitrogen™ PDE3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529481

Catalog No. PIPA529481

Description

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Pig (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).

Specifications

• Antigen: PDE3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE3A
• Gene Alias: A930022O17Rik; C87899; cAMP phosphodiesterase, myocardial cGMP-inhibited; CGI-PDE; CGI-PDE A; CGI-PDE-A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited phosphodiesterase; cyclic GMP-inhibited phosphodiesterase A; cyclic nucleotide phosphodiesterase; HTNB; PDE3A; phosphodiesterase 3A; phosphodiesterase 3A, cGMP inhibited; phosphodiesterase 3A, cGMP-inhibited; RNPDE3A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5139, 54611
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14432, Q9Z0X4
• Gene Symbols: PDE3A
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PDE3A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov