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Invitrogen™ PDE3A Polyclonal Antibody
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Catalog No. PIPA532972
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50 μg
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PIPA532972 50 μg
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Catalog No. PIPA532972 Supplier Invitrogen™ Supplier No. PA532972
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (94%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE3A
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene PDE3A
Gene Accession No. Q14432
Gene Alias A930022O17Rik; C87899; cAMP phosphodiesterase, myocardial cGMP-inhibited; CGI-PDE; CGI-PDE A; CGI-PDE-A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited phosphodiesterase; cyclic GMP-inhibited phosphodiesterase A; cyclic nucleotide phosphodiesterase; HTNB; PDE3A; phosphodiesterase 3A; phosphodiesterase 3A, cGMP inhibited; phosphodiesterase 3A, cGMP-inhibited; RNPDE3A
Gene Symbols PDE3A
Host Species Rabbit
Immunogen Synthetic 19 amino acid peptide from near N-terminus of human PDE3A.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5139
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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