Invitrogen™ PDE3B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110087

Catalog No. PIPA5110087

Description

Immunogen sequence: PLTPFPGFYP CSEIEDPAEK GDRKLNKGLN RNSLPTPQLR RSSGTSGLLP VEQSSRWDRN NGKRPHQEFG ISSQGCYLNG PFNSNLLTIP KQRSSSVSLT HHVGLRRAGV LSSLSPVNSS NHGPVSTGSL TNRSPIEFPD TADFLNKPSV ILQRSLGNAP NTPDFYQQLR NSDSNLCNSC GHQMLKYVST SESDGTDCCS GKSGEEENIF SKESFKLMET QQEEETEKKD SRKLFQEGDK WLTEEAQSEQ QTNIEQEVSL D.

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Specifications

• Antigen: PDE3B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE3B
• Gene Alias: 9830102A01Rik; AI847709; CGIP1; CGI-PDE B; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; PDE3B; phosphodiesterase 3B; phosphodiesterase 3B cGMP inhibited; phosphodiesterase 3B, cGMP-inhibited
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18576, 5140
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13370, Q61409
• Gene Symbols: PDE3B
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human PDE3B (NP_000913.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov