PDE4B Monoclonal Antibody (OTI2B6), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA503439

Catalog No. 50-167-4335

Description

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: PDE4B
• Classification: Monoclonal
• Concentration: 0.91 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q07343
• Gene Symbols: PDE4B
• Immunogen: Full length human recombit protein of human PDE4B produced in HEK293T cell
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2B6
• Conjugate: Unconjugated
• Gene: PDE4B
• Gene Alias: DPDE4, PDEIVB
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5142
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid