PDE4B Mouse anti-Human, Mouse, Clone: OTI1D12, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF503471

Catalog No. 50-166-2159

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: PDE4B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PDE4B
• Gene Alias: DPDE4, PDEIVB
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18578, 5142
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1D12
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q07343
• Gene Symbols: Pde4b
• Immunogen: Full length human recombit protein of human PDE4B produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1