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Invitrogen™ PDE4B Polyclonal Antibody
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Catalog No. PIPA131138
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100 μg
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Catalog No. Quantity
PIPA131138 100 μg
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Catalog No. PIPA131138 Supplier Invitrogen™ Supplier No. PA131138
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Description

Rabbit Polyclonal Antibody

PA1-31138 does not cross react with PDE4B1, PDE4B2 and PDE4B4 nor with PDE4A, PDE4C or PDE4D. Predicted molecular weight: 100 kDa.

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE4B
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.65 mg/mL
Conjugate Unconjugated
Formulation Tris glycine with 0.5% BSA, 30% glycerol and 0.02% Sodium azide; pH 7.4-7.9
Gene PDE4B
Gene Accession No. P14646, Q07343
Gene Alias 3',5'-cyclic AMP phosphodiesterase; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DKFZp686F2182; DPDE4; dunce; dunce-like phosphodiesterase E4; MGC126529; MGC93193; OTTHUMP00000046896; PDE32; PDE4/IVb; PDE4B; Pde4B1; Pde4B2; Pde4B3; Pde4B4; PDEIVB; phosphodiesterase 4B; Phosphodiesterase 4B cAMP-specific (dunce; phosphodiesterase 4B, cAMP specific; phosphodiesterase 4B, cAMP-specific; Phosphodiesterase 4B, cAMP-specific (dunce; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); R74983; RP5-876C12.1
Gene Symbols PDE4B
Host Species Rabbit
Immunogen Synthetic peptide selective only for PDE4B3 subtype.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18578, 24626, 5142
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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