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Invitrogen™ PDE4B Polyclonal Antibody
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Catalog No. PIPA521460
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100 μL
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PIPA521460 100 μL
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Catalog No. PIPA521460 Supplier Invitrogen™ Supplier No. PA521460
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, PC-3, HCT116. Predicted reactivity: Mouse (97%), Rat (96%), Xenopus laevis (86%), Pig (98%), Chicken (89%), Rhesus Monkey (100%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE4B
Applications Western Blot
Classification Polyclonal
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene PDE4B
Gene Accession No. Q07343
Gene Alias 3',5'-cyclic AMP phosphodiesterase; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DKFZp686F2182; DPDE4; dunce; dunce-like phosphodiesterase E4; MGC126529; MGC93193; OTTHUMP00000046896; PDE32; PDE4/IVb; PDE4B; Pde4B1; Pde4B2; Pde4B3; Pde4B4; PDEIVB; phosphodiesterase 4B; Phosphodiesterase 4B cAMP-specific (dunce; phosphodiesterase 4B, cAMP specific; phosphodiesterase 4B, cAMP-specific; Phosphodiesterase 4B, cAMP-specific (dunce; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); R74983; RP5-876C12.1
Gene Symbols PDE4B
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human PDE4B. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5142
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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