PDE4B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5145429

Catalog No. FEPA5145429

Description

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: PDE4B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE4B
• Gene Alias: 3',5'-cyclic AMP phosphodiesterase, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, DKFZp686F2182, DPDE4, dunce, dunce-like phosphodiesterase E4, MGC126529, MGC93193, OTTHUMP00000046896, PDE32, PDE4/IVb, PDE4B, Pde4B1, Pde4B2, Pde4B3, Pde4B4, PDEIVB, phosphodiesterase 4B, Phosphodiesterase 4B cAMP-specific (dunce, phosphodiesterase 4B, cAMP specific, phosphodiesterase 4B, cAMP-specific, Phosphodiesterase 4B, cAMP-specific (dunce, phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila), R74983, RP5-876C12.1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 18578, 24626, 5142
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Isotype: IgG

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
• Gene Accession No.: P14646, Q07343
• Gene Symbols: PDE4B
• Immunogen: Recombinant Rat PDE4B protein, Lys500-Thr736 (Accession #P14646)
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid