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PDE4B Polyclonal Antibody, Invitrogen™

Catalog No. FEPA5145429
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FEPA5145429 200 μL
FEPA5145430 20 μL
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Catalog No. FEPA5145429 Supplier Thermo Scientific Supplier No. PA5145429

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Rabbit Polyclonal Antibody

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDE4B
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene PDE4B
Gene Accession No. P14646, Q07343
Gene Alias 3',5'-cyclic AMP phosphodiesterase, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, DKFZp686F2182, DPDE4, dunce, dunce-like phosphodiesterase E4, MGC126529, MGC93193, OTTHUMP00000046896, PDE32, PDE4/IVb, PDE4B, Pde4B1, Pde4B2, Pde4B3, Pde4B4, PDEIVB, phosphodiesterase 4B, Phosphodiesterase 4B cAMP-specific (dunce, phosphodiesterase 4B, cAMP specific, phosphodiesterase 4B, cAMP-specific, Phosphodiesterase 4B, cAMP-specific (dunce, phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila), R74983, RP5-876C12.1
Gene Symbols PDE4B
Host Species Rabbit
Immunogen Recombinant Rat PDE4B protein, Lys500-Thr736 (Accession #P14646)
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18578, 24626, 5142
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form Liquid
Isotype IgG
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