Invitrogen™ PDE4D Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589542

Catalog No. PIPA589542

Description

Immunogen sequence: FKLLQEENCD IFQNLTKKQR QSLRKMVIDI VLATDMSKHM NLLADLKTMV ETKKVTSSGV LLLDNYSDRI QVLQNMVHCA DLSNPTKPLQ LYRQWTDRIM EEFFRQGDRE RERGMEISPM CDKHNASVEK SQVGFIDYIV HPLWETWADL VHPDAQDILD TLEDNREWYQ STIPQSPSPA PDDPEEGRQG QTEKFQFELT LEEDGESDTE KDSGSQVEED TSCSDSKTLC TQDSESTEIP LDEQVEEEAV GEEEESQPEA CVIDDRSPDT; Positive Samples: HT-29, A-549, SW480; Cellular Location: Apical cell membrane, Cytoplasm, Membrane, centrosome, cytoskeleton, microtubule organizing center.

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.

Specifications

• Antigen: PDE4D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pde4d
• Gene Alias: 9630011N22Rik; ACRDYS2; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D; cAMP-specific phosphodiesterase PDE4D6; cAMP-specific phosphodiesterase splice variant PDE4D8; cyclic AMP specific phosphodiesterase PDE4D5A; DKFZp686M11213; Dpde3; dunce; FLJ97311; HGNC:8783; HS PDE4DN2; HSPDE4D; PDE43; Pde4d; PDE4D3; PDE4D7; PDE4DN2; phosphodiesterase 4D; Phosphodiesterase 4D cAMP-specific (dunce; phosphodiesterase 4D, cAMP specific; phosphodiesterase 4D, cAMP-specific; Phosphodiesterase 4D, cAMP-specific (dunce; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); STRK1; testicular tissue protein Li 136
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24627, 5144
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P14270, Q08499
• Gene Symbols: Pde4d
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 249-518 of human PDE4D (NP_0011841521).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG