Invitrogen™ PDE7A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531117

Catalog No. PIPA531117

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (94%), Rat (94%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: PDE7A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE7A
• Gene Alias: AU015378; AW047537; HCP1; High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; P2A; PDE7; PDE7-1; Pde7a; phosphodiesterase 7A; phosphodiesterase isozyme 7; rolipram-insensitive phosphodiesterase type 7; TM22
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5150
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q13946
• Gene Symbols: PDE7A
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PDE7A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov