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Invitrogen™ PDE7B Polyclonal Antibody
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Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532978

Catalog No. PIPA532978


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Description

Description

Percent identity with other species by BLAST analysis: Human (100%); Gibbon, Monkey (94%); Gorilla, Mouse, Rat, Elephant, Horse, Rabbit (88%); Opossum (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

The 3', 5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3', 5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PDE7B
Polyclonal
Unconjugated
Pde7b
bA472E5.1; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase; MGC88256; Pde7b; phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; RP11-472E5.2
Rabbit
Antigen affinity chromatography
RUO
27115
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.1% sodium azide
Q9NP56
Pde7b
Synthetic 17 amino acid peptide from near N-terminus of human PDE7B.
50 μg
Primary
Human
Antibody
IgG
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