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Invitrogen™ PDE7B Polyclonal Antibody

Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA532978
Description
Percent identity with other species by BLAST analysis: Human (100%); Gibbon, Monkey (94%); Gorilla, Mouse, Rat, Elephant, Horse, Rabbit (88%); Opossum (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
The 3', 5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3', 5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Specifications
PDE7B | |
Polyclonal | |
Unconjugated | |
Pde7b | |
bA472E5.1; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase; MGC88256; Pde7b; phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; RP11-472E5.2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
27115 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
1 mg/mL | |
PBS with 0.1% sodium azide | |
Q9NP56 | |
Pde7b | |
Synthetic 17 amino acid peptide from near N-terminus of human PDE7B. | |
50 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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