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PDGFD Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
$496.07
Specifications
Antigen | PDGFD |
---|---|
Concentration | 0.3 mg/mL |
Applications | Immunohistochemistry (Paraffin) |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-172-9193
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Proteintech Group Inc
140751AP150UL |
150 μL |
Each of 1 for $496.07
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Description
The platelet-derived growth factor (PDGF) family consists of four members; PDGF-A, PDGF-B, PDGF-C and PDGF-D (spinal cord-derived growth factor-B or iris-expressed growth factor). PDGF members form disulphide-bonded dimeric isoforms, which are important for growth, survival and function in several types of connective tissue cells. Their biological effects are mediated via two tyrosine kinase receptors, PDGFR-a and PDGFR-b, and PDGF-mediated signaling is critical for development of many organ systems. PDGF-D has a two-domain structure similar to PDGF-C and is secreted as a disulphide-linked homodimer, PDGF-DD. PDGF-D induces cellular transformation and promotes tumor growth by accelerating the proliferation rate of tumor cells and by stimulation of tumor neovascularization. PDGF-D may play a role in the development of brain tumors. The potential oncogenic activity of PDGF-DD may be important for the development and/or progression of prostate cancer. PDGF-D is expressed in fibroblastic adventitial cells, cultured endothelial cells and in a variety of tumor cell lines including those derived from ovarian, renal and lung cancers, as well as from astrocytomas and medulloblastomas. PDGF-D is expressed in the human kidney.Specifications
PDGFD | |
Immunohistochemistry (Paraffin) | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q925I7, Q9EQT1, Q9GZP0 | |
66018, 71785, 80310 | |
PDGFD Fusion Protein Ag5154 | |
Primary | |
-20°C | |
PDGFD |
0.3 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
IEGF, Iris expressed growth factor, MSTP036, PDGF D, PDGFD, PDGFD receptor binding form, SCDGF B, SCDGFB, UNQ1899/PRO4345 | |
Pdgfd | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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