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PDGFRA Mouse anti-Human, Clone:8E12F2, Abnova™

Catalog No. 89333138 Shop All Abnova Corporation Products
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89-333-138 100 μg
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Catalog No. 89-333-138 Supplier Abnova Corporation Supplier No. MAB16646
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Mouse monoclonal antibody raised against recombinant human PDGFRA.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq]

Specifications

Antigen PDGFRA
Applications ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 8E12F2
Conjugate Unconjugated
Description platelet-derived growth factor receptor, alpha polypeptide
Dilution ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry (1:200-1:1000)
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene PDGFRA
Gene Alias CD140A, MGC74795, PDGFR2, Rhe-PDGFRA
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acid 361-528 of human PDGFRA from E. coli.
Quantity 100 μg
Gene ID (Entrez) 5156
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG1
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