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PDGFRA Polyclonal Antibody, Invitrogen™

Catalog No. PIPA516571
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500 μL
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PIPA516571 500 μL
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Catalog No. PIPA516571 Supplier Thermo Scientific Supplier No. PA516571

Description

Rabbit Polyclonal Antibody

PA5-16571 targets PDGFR alpha in IHC applications and shows reactivity with mouse, Rat, and Human samples. The PA5-16571 immunogen is a synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha.

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDGFRA
Applications Immunocytochemistry, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene PDGFRA
Gene Accession No. P16234, P20786, P26618
Gene Alias AI115593; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; CD140 antigen-like family member A; CD140A; CD140a antigen; GAS9; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGFACE; PDGFR2; Pdgfr-2; PDGFRA; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; platelet derived growth factor receptor alpha; platelet derived growth factor receptor, alpha polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA
Gene Symbols PDGFRA
Host Species Rabbit
Immunogen A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18595, 25267, 5156
Target Species Human, Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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